Plasma Separation Device

2017-02-27 VIEW:



Nanjing BioPoint® has developed a novel, low-cost and instrument-free plasma separator based on lateral flow chromatography, the VLPlasma® device. It provides an integrated solution for separation, collection and drying of cell-free plasma from whole blood, suitable for storage and transport to central laboratories for testing,including HIV viral load (VL) testing and Serological testing for various diseases.

Clinical Trials:
1. Clinical field trial conducted with 198 HIV-infected participants recruited  from the University of Malay Medical Centre, Kuala Lumpur,  Malaysia
2. Three arm comparative study with samples collected as DBS or using the VLPlasma® device, or fresh plasma (reference)
3. VL test run on COBAS® AmpliPrep / COBAS® TaqMan® (Roche)
* Two DBS samples and three FDPS samples failed to give results
The clinical results showed that the accuracy of VL testing was significantly improved by VLPlasma® compared with the DBS method. The results demonstrate the device has successfully obtained cell free plasma suitable for applications such as HIV viral load test.
Further Studies :
Expanded applications of the VLPlasma® device in other infectious disease diagnostics are being explored in studies at the Burnet Institute, Melbourne, Australia, supported by the Bill & Melinda Gates Foundation (Grand Challenges Explorations, Round 20). 
Intellectual Property:
Patent application PCT/AU2015/050715, under exclusive license to Nanjing BioPoint Diagnostic Technology Co. Ltd., a spinoff company formed by the Burnet Institute.